| Preface |
vii |
| Chapter 1. Anatomy and Physiology of the Skin |
1 |
| Introduction |
1 |
| Epidermis |
2 |
| The Regulation of Epidermal Proliferation and Differentiation |
3 |
| Nonkeratinocyte Cells of the Epidermis |
4 |
| The Dermal-Epidermal Junction |
5 |
| Epidermal Appendages |
5 |
| The Dermis |
8 |
| Subcutaneous Fat |
10 |
| Summary |
10 |
| References |
10 |
| Chapter 2. Nonmelanoma Skin Cancer |
13 |
| Definition |
13 |
| Incidence |
13 |
| Pathogenesis |
13 |
| Risk Factors |
13 |
| Basal Cell Carcinoma |
16 |
| Squamous Cell Carcinoma |
20 |
| Diagnosis and Workup of Nonmelanoma Skin Cancer |
25 |
| Staging |
26 |
| Treatment of Nonmelanoma Skin Cancer: Basal Cell Carcinoma and Squamous Cell Carcinoma |
26 |
| Prognosis for Nonmelanoma Skin Cancer: Basal Cell Carcinoma and Squamous Cell Carcinoma |
33 |
| Merkel Cell Carcinoma |
33 |
| Dermatofibrosarcoma Protuberans |
39 |
| Kaposi Sarcoma |
41 |
| Prevention |
43 |
| Research |
45 |
| Targeted Therapies |
45 |
| Summary |
45 |
| References |
47 |
| Chapter 3. Melanoma |
51 |
| What Is Melanoma? |
51 |
| Incidence |
51 |
| Classification/Type |
51 |
| Melanoma Subtypes |
54 |
| Skin Pigmentation Abnormalities |
55 |
| Pathophysiology |
56 |
| Risk Factors |
56 |
| Prevention and Detection |
58 |
| Patient Assessment |
59 |
| Diagnosis |
60 |
| Prognosis |
61 |
| Staging |
61 |
| Regional Lymph Nodes |
63 |
| Distant Metastases |
64 |
| Treatment Modalities |
65 |
| Patient Follow-Up |
70 |
| Patient Education |
71 |
| Psychosocial Issues |
71 |
| Summary |
73 |
| References |
73 |
| Chapter 4. Cutaneous T-Cell Lymphoma: Mycosis Fungoides/Sézary Syndrome |
81 |
| Introduction |
81 |
| Epidemiology |
81 |
| Pathophysiology |
82 |
| Staging |
83 |
| Patient Assessment |
83 |
| Treatment Modalities |
87 |
| Patient Management and Evaluation |
93 |
| Survivor Issues |
98 |
| Summary |
98 |
| References |
99 |
| Index |
113 |