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Lung Cancer Clinical Resource Area - Diagnosis

Signs and Symptoms

Individuals who have lung cancer frequently experience these symptoms:

  • Cough (persistent, dry)
  • Shortness of breath
  • Wheezing
  • Chest pain
  • Hemoptysis (bloody, coughed-up sputum)
  • Anorexia and weight loss
  • Frequent pneumonias
Other symptoms that are associated with advanced lung cancer include:
  • Fatigue
  • Chills
  • Swallowing difficulties
  • Speech difficulties or changes (e.g., hoarseness)
  • Clubbing of the finger tips
  • Skin paleness or bluish discoloration
  • Muscle contractions or atrophy (shrinkage)
  • Joint pain
  • Facial swelling or paralysis
  • Eyelid drooping
  • Bone pain
  • Gynomastia

Diagnostic Tests
  • Physical exam: A thorough physical examination with attention to the chest and thoracic lymph nodes and sputum sample. If sputum analysis does not provide a definite diagnosis, biopsy is required.
  • Chest X-ray
  • CT scan of the chest
  • MRI of the chest
  • MRI of the chest
  • Bronchoscopy: To obtain washings of the respiratory tissues. If the bronchoscopy is negative, proceed to a needle biopsy.
  • Needle biopsy: Fine needle aspiration (FNA) uses a slim, hollow needle that is attached to a syringe. Large needle or core biopsy uses a larger needle. Mediastinoscopy. Used to rule out metastatic disease and sample mediastinal nodes.
  • Tumor markers
  • PTH (parathyroid hormone)
  • CEA (carcinogenic antigen). A CEA level greater than 50 may indicates advanced diseases.
  • CYFRA21-1 (cytokeratin fragment 19)

Pathology

Non-small cell lung cancer (NSCLC) includes three histologies:
  • Epidermoid or squamous carcinoma
  • Adenocarcinoma
  • Large cell carcinoma

Nursing Diagnosis

  • Knowledge deficit r/t lung cancer
  • Anxiety
  • Pain
  • Impaired gas exchange
  • Impaired tissue integrity
  • Ineffective airway clearance
  • Anticipatory grieving
  • Risk for fluid volume excess