Antiemetic Guidelines: Using Education to Improve Adherence and Reduce Incidence of CINV in Patients Receiving Highly Emetogenic Chemotherapy

Corrine Mellin

Mallory Lexa

Ashley Leak Bryant

Susie Mason

Deborah K. Mayer

guideline, chemotherapy, provider, adherence, CINV, antiemetic
CJON 2018, 22(3), 297-303. DOI: 10.1188/18.CJON.297-303

Background: With the development of increasingly effective antiemetic regimens, guideline adherence can prevent 70%–80% of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer.

Objectives: This quality improvement project aims to increase rates of adherence to national guidelines and, ultimately, decrease rates of CINV experienced by patients receiving highly emetogenic chemotherapy.

Methods: A retrospective chart analysis was performed. In-person education was provided to staff nurses and advanced practice providers on guidelines, followed by a survey immediately postintervention and again at three months.

Findings: Prior to the intervention, 49% of patients were found to experience CINV, with only 7% receiving guideline-appropriate prophylaxis. At three months, 37% of patients experienced CINV, with 22% receiving appropriate prophylaxis.

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