Evolving Foundations

Hypofractionated Radiation: Understanding the Modality and Impact on Patient Outcomes

Ashley Cothran

Julie C. Martin
radiation, radiation therapy, hypofractionation, hypofractionated

CJON 2022, 26(1), 23-26. DOI: 10.1188/22.CJON.23-26

The evolving field of radiation oncology has revolutionized treatment options for several malignancies. Advances in technology allow radiation oncologists to maximize the dose of radiation while minimizing damage to surrounding healthy tissue. Hypofractionated radiation, which reduces the frequency and number of treatments, is being studied in multiple tumor types. This modality often shortens a course of therapy by days or even weeks. Staying informed on emerging treatment modalities allows oncology nurses to educate patients on treatment plans and potential toxicities. This article explains the differences in radiation therapy modalities and focuses on hypofractionation and its benefits to patients.


  • Advancements in radiation technology have led to decreased toxicities and improved patient outcomes.
  • Hypofractionated therapy maximizes the dose of radiation and minimizes toxicity to organs at risk.
  • Oncology nurses must focus on the area being treated with radiation therapy when educating patients on possible side effects.
Members Only
Not a current ONS member or journal subscriber?

Purchase This Article

Receive a PDF to download and print.