CDK4/6 Inhibitor Learning Library

CDK4/6 Inhibitor Learning Library

Check out resources such as case studies, practice resources, patient education resources, and videos in our CDK4/6 inhibitor learning library. Find tools to help you with your shared decision-making conversations, oral adherence strategies to ensure your patients are taking their medication correctly at home, an easy-to-read dose adjustment guide, and more.

Learning Activities

CDK4/6 Inhibitor Case Study Series Bundle
This series of interactive case studies will guide you through scenarios of patients with HR+, HER2- advanced or metastatic breast cancer. It will introduce practice resources to help with selecting the right CDK4/6 inhibitor, guide dose adjustments, and strategies for oral adherence. Focus on the areas you are most interested in by taking just 1 or all 6 of the case studies. Have the opportunity to practice monitoring and management of CDK4/6 inhibitor therapy in a safe virtual environment and learn how you can utilize the CDK4/6 inhibitor resource curated for nurses just like you.

Innovations in Metastatic Breast Cancer Care Video Series
This series of videos walks you through treatment options for advanced or metastatic breast cancer, including combined modality regimens. Early intervention approaches for common adverse reactions from CDK4/6 inhibitors. This will include assessment tools, symptom management, and recommendations for dose modification. Along with strategies and resources that will build upon existing skills to discern and offer optimal patient-centered treatment options.

The Case of the CTCAE Assessment for CDK4/6 Adverse Events
Review this case study to help familiarize yourself on how to monitor and manage your patients taking CDK4/6 inhibitor therapy. Mrs. Jones is a 66-year-old postmenopausal woman who developed left breast pain and a palpable mass. A mammogram and ultrasound showed a 4.6 cm mass with an enlarged axillary node. A core biopsy revealed invasive ductal carcinoma that is estrogen receptor positive, progesterone receptor positive, and HER2 negative. Positron-emission tomography and computed tomography scans revealed metastatic disease.

Practice Resources

Advance Care Planning Worksheet
Advance care planning is a term used to describe a conversation between patients, their families, and healthcare providers about future wishes and priorities for care. It helps the patient contemplate their future, consider their sense of purpose and core values, catalyze deeper communication with their loved ones, and puts the power back in the patient’s hands to ensure their needs and preferences will be honored when it matters most. Use this questionnaire or share it with a loved one or patient to start the advance care planning process. 


Dual Inhibition of ER+ Metastatic Breast Cancer: Anti-hormonal Therapy + CDK 4/6 Inhibitor
This resource uses easy to interpret visualize graphics to help better understand the mechanism of action when combining anti-hormonal therapy and a CDK4/6 inhibitor as a dual inhibitor to treat metastatic breast cancer.

CDK4/6 Inhibitors Administration Checklist
If your HR+ HER2- metastatic breast cancer patient is prescribed a CDK4/6 inhibitor, use this checklist to ensure that you have completed the appropriate initial assessments and tests.

CDK4/6 Inhibitor Dosing Guide
This resource is intended to guide providers caring for patients that have HR+ HER2- metastatic breast cancer and are receiving CDK4/6 inhibitors for their treatment and are experiencing adverse reactions that indicate a need for dose adjustment. Reference these easy to interpret dosing guides.

HR+ Metastatic Breast Cancer Targeted Therapy Profiles
This table helps compare the differences between the 3 FDA approved CDK4/6 inhibitors and a mTOR inhibitor. Use this resource as a shared decision-making tool to help your patients understand the different therapy options so they can work with you to choose what is best for them.

Palliative Care Communication Strategies
Use these communication techniques with your patients when you need to start palliative care conversations, choose a new treatment plan, or discuss end of life.

Patient Education Resource

Oral Chemotherapy Education Sheets
Empower your patients to take a more active role in their cancer treatment with free oral chemo patient education sheets that answer common drug-related questions, developed by the National Community Oncology Dispensing Association, Inc., Association of Community Cancer Centers, Hematology Oncology Pharmacy Association, and ONS.

Videos

Advance Care Planning DrawShop Video
Advance care planning is a term used to describe a conversation between patients, their families, and healthcare providers about future wishes and priorities for care. It helps the patient contemplate their future, consider their sense of purpose and core values, catalyze deeper communication with their loved ones, and puts the power back in the patient’s hands to ensure their needs and preferences will be honored when it matters most. Learn more about advance care planning through this video.

How do CDK4/6 Inhibitors Work Video
Explains the mechanism of action or CDK4/6 inhibitor, a targeted therapy used in the treatment of HR+, HER2- metastatic breast cancer.

Nursing Considerations when Administering CDK4/6 Inhibitors Video
After your patient is prescribed a CDK4/6 inhibitor, use this video to ensure that you have completed the appropriate initial assessment and tests.

Oral Adherence DrawShop Video
Use these communication techniques with your patients when you need to start palliative care conversations, choose a new treatment plan, or discuss end of life.
 

ONS Clinical Practice Resources

Use these resources to inform and support your clinical practice.

View All Clinical Practice Resources