CINV Search Strategy

CINV SEARCH STRATEGY AND RESULTS
 
Initial references prior to update: 42
 
Databases searched for update: PubMed, CINAHL, Cochrane Collaboration, and NCCN
 
Search results of literature retrieved 1/1/2009–9/1/2015:
  • PubMed
    • CINV[ti] OR ((cancer OR chemotherapy) AND "Nausea/chemically induced"[MeSH Terms]) OR (chemotherapy[ti] AND (nausea[ti] OR vomiting[ti] OR antiemetic*[ti])) OR (((casopitant[ti] OR palonosetron[ti] OR ramosetron[ti] OR olanzapine[ti] OR antagonist*[ti] OR aprepitant[ti] OR granisetron[ti] OR ((acupuncture[ti] OR acupressure[ti]) AND (CINV[ti] OR nausea[ti] OR vomiting[ti])) OR cinv[ti] OR (cancer[ti] AND nausea[ti]) OR (chemotherapy[ti] AND nausea[ti])) AND (systematic[ti] OR trial*[ti]))) OR (CINV[ti] OR ((cancer OR chemotherapy) AND "Nausea/chemically induced"[MeSH Terms]) OR (chemotherapy[ti] AND (nausea[ti] OR vomiting[ti] OR antiemetic*[ti])) AND systematic[sb]) OR (("chemotherapy-induced nausea and vomiting" OR CINV) AND (Therapy/Broad[filter])) AND ("2009/01/01"[PDAT] : "2015/09/01"[PDAT])
    • 2213 citations retrieved
  • CINAHL
    • TI CINV OR ((chemotherap* OR cancer* OR neoplasm OR lymph* OR malignan* OR tumor OR tumour OR leukemia OR sarcoma OR myeloma OR carcinoma OR MJ antineoplastic OR MJ oncolog*) AND (MH "Nausea and Vomiting/CI" OR MH "Anticipatory Nausea and Vomiting/CI" OR MH "Nausea/CI" OR MH "Vomiting/CI" OR TI CINV OR TI nausea OR TI vomiting OR antiemetic* OR “anti-emetic*”)) OR ((TI alprazolam OR TI lorazepam OR TI corticosteroid* OR TI 5-HT3 OR TI NK1 OR TI “NK 1*” OR TI dolasetron OR TI granisetron OR TI ondansetron OR TI tropisetron OR TI palonosetron OR TI ramosetron OR TI antagonist* OR TI aprepitant OR TI fosaprepitant OR TI casopitant OR TI dexamethasone OR TI steroid* OR TI neurokinin* OR TI phenothiazine OR TI metoclopramide OR TI butyrophenones OR TI haloperidol OR TI serotonin OR TI prochlorperazine OR TI promethazine OR TI cannabinoid* OR TI dronabinol OR TI nabilone OR TI marijuana OR TI THC OR TI cannabis OR TI benzodiazepine OR TI benzamide OR TI music* OR TI guided imagery OR TI megestrol OR TI “virtual reality” OR TI acupuncture OR TI acupressure OR TI acustimulation OR TI “grape juice” OR TI ginger OR TI herb* OR TI massage OR TI aromatherap* OR TI yoga OR TI olanzapine OR TI mirtazapine) AND (MH "Nausea and Vomiting/CI" OR MH "Anticipatory Nausea and Vomiting/CI" OR MH "Nausea/CI" OR MH "Vomiting/CI" OR TI CINV OR TI nausea OR TI vomiting OR antiemetic* OR “anti-emetic*”) AND (chemotherap* OR cancer* OR neoplasm OR lymph* OR malignan* OR tumor OR tumour OR leukemia OR sarcoma OR myeloma OR carcinoma OR MJ antineoplastic OR MJ oncolog*))
    • 859 citations retrieved
372 titles were selected for a full article review.
 
296 final studies were included after the removal of duplicates and studies that did not meet inclusion criteria and the addition of manuscripts retrieved in other topics meeting chemotherapy-induced nausea and vomiting-specific criteria.
 
Inclusion Criteria: 
1. Full research report, systematic review, guideline, or meta-analysis
2. Study must report results of measurement of chemotherapy-induced nausea and vomiting
3. The study examines an intervention aimed at affecting chemotherapy-induced nausea and vomiting
4. Study sample must include patients with cancer
5. Include pediatric as well as adult studies
6. As of 1/1/2016, additional inclusions are (a) sample size of at least 40 or 20 per study group, and (b) for complex interventions, the description of the intervention must be sufficient to identify the components of that intervention.
 
Exclusion Criteria: 
1. Grey literature
2. Descriptive studies
3. Studies involving nausea and vomiting associated with surgery or otherwise unrelated to chemotherapy administration

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