CINV Search Strategy

Search Dates: Search results of literature retrieved March 2009–September 2014

Databases searched were PubMed, CINAHL, Cochrane Collaboration, National Comprehensive Cancer Network (NCCN) (Note – when available, EMBASE was also included, because chemotherapy-induced nausea and vomiting [CINV] is a medication-intensive topic for interventions.)

Search keywords were CINV[ti] OR ((cancer OR chemotherapy) AND "Nausea/chemically induced"[MeSH Terms]) OR (chemotherapy[ti] AND (nausea[ti] OR vomiting[ti] OR antiemetic*[ti])) OR (((casopitant[ti] OR palonosetron[ti] OR ramosetron[ti] OR olanzapine[ti] OR antagonist*[ti] OR aprepitant[ti] OR granisetron[ti] OR ((acupuncture[ti] OR acupressure[ti]) AND (CINV[ti] OR nausea[ti] OR vomiting[ti])) OR cinv[ti] OR (cancer[ti] AND nausea[ti]) OR (chemotherapy[ti] AND nausea[ti])) AND (systematic[ti] OR trial*[ti]))) OR (CINV[ti] OR ((cancer OR chemotherapy) AND "Nausea/chemically induced"[MeSH Terms]) OR (chemotherapy[ti] AND (nausea[ti] OR vomiting[ti] OR antiemetic*[ti])) AND systematic[sb]) OR (("chemotherapy-induced nausea and vomiting" OR CINV) AND (Therapy/Broad[filter]))

Studies were included in the review if they

  • Were full research reports, systematic reviews, guidelines, or meta-analyses.
  • Reported results of measurement of CINV.
  • Examined interventions aimed at affecting CINV.
  • Included patients with cancer.
  • Included pediatric as well as adult studies.

Studies were excluded from the review if they were 

  • Grey literature
  • Descriptive studies
  • Studies involving nausea and vomiting associated with surgery, or otherwise not related to chemotherapy administration.

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