Fatigue Search Strategy

  • Initial references prior to update – 122
  • Search results of literature retrieved 5/1/2008 – 11/30/2015
  • PubMed:
  • (fatigue in patients with cancer) AND (randomized controlled trial[Publication Type] OR (randomized[Title/Abstract] AND controlled[Title/Abstract] AND trial[Title/Abstract]))
  • Filters activated: Publication date from 2008/05/01 to 2015/11/30
  • 647 citations
  • (Therapy/Broad[filter] OR systematic[sb]) AND ((Fatigue[majr] OR fatigue[ti]) AND (chemotherapy OR cancer OR oncolog* OR neoplasms[majr]))
  • Filters activated: Publication date from 2008/05/01 to 2015/11/30
  • 814 citations
  • (MH "Cancer Fatigue" OR MM fatigue OR TI fatigue ) AND (chemotherapy OR cancer OR oncolog* OR neoplasms)
  • Limiters: Published Date: 20080501-20151130, English Language, Clinical Queries: Therapy - High Sensitivity, Therapy - High Specificity, Therapy - Best Balance
  • 442 citations
  • 243 titles selected for full article review
  • 176 final publications included after removal of duplicates and studies that did not meet inclusion criteria, and addition of manuscripts retrieved in other topics meeting topic specific criteria
  • NCCN  
  • NCCN Clinical Practice Guidelines in Oncology: Cancer-related fatigue [v.1.2014]
Inclusion Criteria: 
1. Full research report, systematic review, guideline or meta-analysis
2. Study must report results of measurement of fatigue
3. The study examines an intervention aimed at affecting the symptom of fatigue
4. Study sample must include adolescent or adult patients with cancer.
Exclusion Criteria: 
1. Grey literature
2. Descriptive only study