Pain Search Strategy

PAIN SEARCH STRATEGY AND RESULTS
 
Initial references prior to update: 34
 
Databases searched for update: PubMed, CINAHL, Cochrane Collaboration, and NCCN
 
Search results of literature retrieved 1/1/2009–4/29/2015:
  • PubMed
    • (pain[ti] AND cancer[ti]) OR ((pain[ti] OR pain[majr]) AND neoplasms[majr]) AND (("2009/01/01"[PDAT] : "2015/4/29"[PDAT]) AND "humans"[MeSH Terms] AND English[lang] AND cancer[sb])
    • 3,809 citations retrieved
  • CINAHL
    • (MH "Cancer Pain" OR (TI cancer AND TI pain)) OR ( MM pain AND (cancer OR neoplasms OR oncolog*)) 
    • Limiters: English Language; Clinical Queries: Therapy - High Sensitivity, Therapy - High Specificity, Therapy - Best Balance
    • 1,090 citations retrieved
  • Cochrane Collaboration
    • Arcidiacono, P.G., Calori, G., Carrara, S., McNicol, E.D., & Testoni, P.A. (2011). Celiac plexus block for pancreatic cancer pain in adults. Cochrane Database of Systematic Reviews, 2011(3). doi:10.1002/14651858.CD007519.pub2
    • Ballantyne, J.C., & Carwood, C.M. (2005). Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. Cochrane Database of Systematic Reviews, 2005(2). doi:10.1002/14651858.CD005178
    • Bell, R., Eccleston, C., & Kalso, E. (2003). Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database of Systematic Reviews, 2003(1). doi:10.1002/14651858.CD003351
    • Bell, R., Eccleston, C., & Kalso, E.A. (2012). Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database of Systematic Reviews, 2012(11). doi:10.1002/14651858.CD003351.pub2
    • Bradt, J., Dileo, C., Grocke, D., & Magill, L. (2011). Music interventions for improving psychological and physical outcomes in cancer patients. Cochrane Database of Systematic Reviews, 2011(8). doi:10.1002/14651858.CD006911.pub2
    • Cepeda, M.S., Carr, D.B., Lau, J., & Alvarez, H. (2010). Music for pain relief. Cochrane Database of Systematic Reviews, 2010(8). doi:10.1002/14651858.CD004843.pub2
    • Challapalli, V., Tremont-Lukats, I.W., McNicol, E.D., Lau, J., & Carr, D.B. (2005). Systemic administration of local anesthetic agents to relieve neuropathic pain. Cochrane Database of Systematic Reviews, 2005(4). doi:10.1002/14651858.CD003345.pub2
    • Hurlow, A., Bennett, M.I., Robb, K.A., Johnson, M.I., Simpson, K.H., & Oxberry, S.G. (2012). Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults. Cochrane Database of Systematic Reviews, 2012(3). doi:10.1002/14651858.CD006276.pub3
    • Lihua, P., Su, M., Zejun, Z., Ke, W., & Bennett, M.I. (2013). Spinal cord stimulation for cancer-related pain in adults. Cochrane Database of Systematic Reviews, 2013(2). doi:10.1002/14651858.CD009389.pub2
    • Martinez-Zapata, M.J., Roque, M., Alonso-Coello, P., & Catala, E. (2006). Calcitonin for metastatic bone pain. Cochrane Database of Systematic Reviews, 2006(3). doi:10.1002/14651858.CD003223.pub2
    • McNichol, E., Strassels, S.A., Goudas, L., Lau, J., & Carr, D.B. (2005). NSAIDs or paracetamol, alone or combined with opioids for cancer pain. Cochrane Database of Systematic Reviews, 2005(2). doi:10.1002/14651858.CD.005180
    • Nicholson, A.B. (2009). Methadone for cancer pain. Cochrane Database of Systematic Reviews, 2009(4). doi:10.1002/14651858.CD003971.pub3
    • Paley, C.A., Johnson, M.I., Tashani, O.A., & Bagnall, A.M. (2011). Acupuncture for cancer pain in adults. Cochrane Database of Systematic Reviews, 2011(1). doi:10.1002/14651858.CD007753.pub2
    • Robb, K.A., Bennett, M.I., Johnson, M.I., Simpson, K.J., & Oxberry, S.G. (2008). Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults. Cochrane Database of Systematic Reviews, 2008(3). doi:10.1002/14651858.CD006276.pub2
    • Wiffen, P.J., & McQuay, H.J. (2010). Oral morphine for cancer pain. Cochrane Database of Systematic Reviews, 2010(8). doi:10.1002/14651858.CD003868.pub2
    • Wong, R.K.S., & Wiffen, P.J. (2009). Bisphosphonates for the relief of pain secondary to bone metastases. Cochrane Database of Systematic Reviews, 2009(4). doi:10.1002/14651858.CD002068
    • Yuen, K.K., Shelley, M., Sze, W.M., Wilt, T., & Mason, M.D. (2006). Bisphosphonates for advanced prostate cancer. Cochrane Database of Systematic Reviews, 2006(4). doi:10.1002/14651858.CD006250
    • Zeppetella, G., & Ribeiro, M.D.C. (2008). Opioids for the management of breakthrough (episodic) pain in cancer patients. Cochrane Database of Systematic Reviews, 2008(1). doi:10.1002/14651858.CD004311.pub2
  • NCCN
    • National Comprehensive Cancer Network. (2011). NCCN Clinical Practice Guidelines in Oncology: Adult cancer pain [v. 2.2011]. Retrieved from http://www.nccn.org/professionals/physician_gls/pdf/pain.pdf
524 titles were selected for a full article review.
 
358 final studies were included after the removal of duplicates and studies that did not meet inclusion criteria and the addition of manuscripts retrieved in other topics meeting pain-specific criteria.
 
Inclusion Criteria: 
1. Full research report, systematic review, guideline, or meta-analysis
2. Study must report results of measurement of pain, including acute, chronic, breakthrough or intractable pain 
3. The study examines a pharmacologic or nonpharmacologic intervention aimed at affecting pain
4. Study sample must include patients with cancer
5. Include pediatric as well as adult studies
6. Studies aimed at the treatment of pain (may include other symptoms) rather than the treatment of the cancer (added 8/2014; team to test out this inclusion criteria)
7. As of 1/1/2016, additional inclusions are (a) sample size of at least 40 or 20 per study group, and (b) for complex interventions, the description of the intervention must be sufficient to identify the components of that intervention.
 
Exclusion Criteria: 
1. Grey literature
2. Descriptive studies
3. New studies involving the use of standard short-acting, sustained, or extended-release opioids will not be included as of 7/2013. Only studies involving new formulations or unusual uses of these medications will be included.
4. Studies involving the examination of effects of different types of surgical anesthesia
5. As of 8/2014, additional exclusions are (a) studies involving surgical procedures such as cordotomy or vertebroplasty, and (b) studies with sample sizes < 30

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