Low Level Laser Therapy

Low Level Laser Therapy

PEP Topic 

Low level laser therapy (LLLT) involves the use of a hand-held infrared laser in an attempt to affect cells and physical symptoms often related to inflammation. This therapy has been approved by the U.S. Food and Drug Administration for the treatment of postmastectomy lymphedema. LLLT also has been evaluated for the prevention and treatment of mucositis in patients receiving stem cell transplantation conditioning or radiation therapy to the oral cavity area. For mucositis, LLLT is defined as a wavelength at 650 nm with a power of 40 mW, and each square centimeter is treated with sufficient time to deliver a tissue energy dose of 2 J/cm2.

Lalla, R.V., Bowen, J., Barasch, A., Elting, L, Epstein, J., Keefe, D.M., . . . Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology. (2014). MASCC/ISOO evidence based clinical practice guidelines for mucositis secondary to cancer therapy. Cancer, 120, 1453–1461. doi:10.1002/cncr.28592

Recommended for Practice

Research Evidence Summaries

Systematic Review/Meta-Analysis

Guideline/Expert Opinion