Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

PEP Topic 
Chronic Pain

Nonsteroidal anti-inflammatory drugs (NSAIDs), or aspirin-like medications, reduce inflammation (and hence pain) arising from injured tissue. Such medications have analgesic, anti-inflammatory, and antipyretic effects, and they inhibit platelet aggregation by inhibiting the cyclooxygenase (COX) enzyme. NSAIDs are associated with adverse gastrointestinal effects, particularly with long-term use.  Most NSAIDs are taken by mouth. NSAIDs are also available for topical use, although topical effects are unknown.

Recommended for Practice

Guideline/Expert Opinion

Systematic Review/Meta-Analysis