Oxycodone/Naloxone

Oxycodone/Naloxone

PEP Topic 
Chronic Pain
Description 

Oxycodone is an opiate analgesic. Naloxone is a competitive opioid-receptor antagonist. At therapeutic oral doses, naloxone exerts a local inhibitory effect on opioid action in the gastrointestinal system. Researchers have studied oxydocone-naloxone, a combination medication, in regard to pain management and in regard to potential to reduce gastrointestinal side effects, such as constipation, in patients who require opioids for pain management.

Recommended for Practice

Research Evidence Summaries


Menu