Triple Drug Regimen

Triple Drug Regimen

PEP Topic 
Chemotherapy-Induced Nausea and Vomiting—Adult
Description 

The triple drug regimen of steroid (dexamethasone), a serotonin 5-HTreceptor antagonist (RA), and a neurokinin 1 (NK1) receptor antagonist has been studied for prevention and management of CINV in patients with cancer receiving multiday chemotherapy regimens. This combination has been recommended by National Comprehensive Cancer Network (NCCN) for patients receiving high emetic risk IV chemotherapy.

Recommended for Practice

Guideline/Expert Opinion

Research Evidence Summaries

Systematic Review/Meta-Analysis


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