Massage therapy involves the manipulation of the soft-tissue with various hand movements (e.g., rubbing, kneading, pressing, rolling, slapping, tapping). Massage therapy can elicit a relaxation response as measured by decreases in heart rate, blood pressure, and respiration. Often, massage is complemented with aromatherapy (i.e., essential oils combined with a carrier cream or oil to manipulate the soft tissues). Aromatherapy has been used together with massage in some studies. An aromatherapy massage is massage therapy delivered by a therapist while aromatherapy oils are administered by inhalation. Massage with or without aromatherapy has been studied in patients with cancer for management of anxiety, caregiver strain and burden, constipation, chemotherapy-induced nausea and vomiting, depression, lymphedema, pain, sleep-wake disturbances, and fatigue.