Polyethylene Glycol (PEG)

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Polyethylene glycol (PEG) is a type of osmotic laxative. In the United States, standard-dose PEG with electrolytes is known as Golytely® (PEG 3350 and electrolytes for oral solution) and Colyte®. Low-dose PEG, referred to as PEG 3350, is available in the United States without electrolytes and is marketed as Miralax®. In the United Kingdom and the Netherlands, PEG is available with or without electrolytes. Nulytely® is a sodium-free mixture for specific patient populations. Regardless of the ingredients, PEG acts by opposing water absorption from stool in the large bowel, increasing the water content and volume of the stools, thus making them softer and easier to pass.