At low doses, prochlorperazine is used to control nausea and vomiting associated with radiation therapy and very low to moderately emetogenic chemotherapy. The drug can be used at high doses to control nausea and vomiting associated with highly emetogenic chemotherapy. It may be particularly effective in the management of delayed nausea and vomiting. Prochlorperazine can be used in both adult and pediatric (more than 2 years of age and 10 kg) populations. This drug belongs to the phenothiazines drug class and is a dopaminergic antagonist. It  can be administered orally, via IV, intramuscularly, or as a rectal suppository. Additional uses for prochorperazine include the treatment of schizophrenia and anxiety. Side effects include extrapyramidal side effects, sedation, and hypotension.