Progressive muscle relaxation (PMR) is a technique of alternately tensing and relaxing muscles groups in sequence throughout the body. When going through muscle groups, individuals can start with the head and neck and progress to the feet, or vice versa. Similarly individuals may do one side of the body at a time, or both sides at the same time. Listening to a prerecorded script may be used to guide individuals through the process. Addition of guided imagery to PMR involves use of mental visualization and use of imagination to enhance relaxation and alter specific experiences and may or may not include direct suggestion. Individuals may use recorded scripts to guide the creation of mental images. Guided imagery can integrate techniques founded in multiple psychological theory and hypnotherapy. PMR with guided imagery has been examined for effectiveness in patients with cancer for chemotherapy-induced nausea and vomiting, anxiety, fatigue, sleep-wake disturbances, and pain.
Naaman, S.C., Radwan, K., Fergusson, D., & Johnson, S. (2009). Status of psychological trials in breast cancer patients: A report of three meta-analyses. Psychiatry, 72, 50–69.
To determine the overall efficacy and magnitude of clinical benefit of psychological interventions in patients with breast cancer, specifically looking at three outcome variables: anxiety, depression, and quality of life (QOL)
Databases searched were MEDLINE (1966–January 2004), EMBASE (1980–2004), Cochrane Controlled Trials Register (1985–February 2004), PsycLit (1973–2004), Biological Abstracts (1990–December 2003), CancerLit (1975–October 2002), CINAHL (1982–December 2003), and Health Star (1975–January 2004).
Search keywords were randomized clinical trial and breast cancer and psychological interventions (cognitive behavioral therapy, group psychotherapy, relaxation, supportive therapy, visual imagery) and psychological adjustment (anxiety, depression, maladjustment, distress, quality of life).
Studies were included in the review if they
Trials examining efficacy of interventions designed to assuage surgical distress were excluded.
Cook, T.D., & Campbell, D.T. (1979). Quasi-experimentation: Design and analysis issues for field settings. Boston, MA: Houghton Mifflin.
Anxiety
Depression
Quality of Life
Overall ES trends among the three outcomes show that more reliable studies were associated with smaller gains. Interventions targeted to patients with clinically important levels of anxiety or depression tended to reap the most benefit, compared to patients who undergo treatment on a prophylactic basis. Group psychotherapy appears to be superior to individual therapy in the treatment of both anxiety and depression. However, a direct impact of group therapy on QOL was not supported in this analysis. CBT interventions appeared to be equally as effective as supportive-experiential therapies. Interventions need not span beyond 20 hours to produce statistically significant ES.
The quality of most studies was not high.
Future trials in psychosocial oncology should incorporate methodological features to enhance internal validity. Evaluation of statistically significant findings on psychometric testing may not reflect clinically significant findings and vice versa. This underscores the need for incorporating qualitative analysis in future studies. There is an absence of studies examining the efficacy of short-term interventions on QOL in advanced breast cancer and should be addressed in future research. Short-term, group interventions may provide the best utilization of scarce resources for the most effect; however, they should be targeted to those patients experiencing clinically important levels of distress. Findings point to the need for higher quality research design and reporting in this field.
Charalambous, A., Giannakopoulou, M., Bozas, E., & Paikousis, L. (2015). A randomized controlled trial for the effectiveness of progressive muscle relaxation and guided imagery as anxiety reducing interventions in breast and prostate cancer patients undergoing chemotherapy. Evidence-Based Complementary and Alternative Medicine, 2015, 270876.
To test the effectiveness of progressive muscle relaxation (PMR) and guided imagery as stress-reducing interventions
Patients randomized to usual care had weekly meetings with psychologists. Those randomized to PMR and guided imagery had four supervised sessions and daily self-practice for three weeks. To stimulate imagery, the guided imagery component included auditory, tactile, and olfactory images. The imagery script was accompanied by music. The intervention was tested and measured with biofeedback prior to study use. Both groups were assessed at baseline and at the end of three weeks. Daily text message reminders were sent to the intervention group to remind them to practice PMR.
The group had a decrease in mean anxiety score whereas the control group had an increase in anxiety at three weeks compared to baseline. The difference between groups of this change was significant (p < 0.001). The same pattern of change between groups was shown for depression (p < 0.001). Salivary amylase and cortisol levels were directly related to anxiety and depression scores (p < 0.001).
PMR and guided imagery were associated with reduced anxiety and depression among patients with breast and prostate cancer during chemotherapy.
Findings here showed that progressive muscle relaxation and guided imagery were effective in reducing anxiety and depression during chemotherapy treatment. These are very low-risk interventions that can be helpful and can be readily incorporated into standard patient care.
Kovacic, T., Zagoricnik, M., & Kovacic, M. (2013). Impact of relaxation training according to the Yoga In Daily Life® system on anxiety after breast cancer surgery. Journal of Complementary and Integrative Medicine, 10, 1–12.
To evaluate the immediate and short-term effects of relaxation training with the Yoga in Daily Life program on anxiety in patients with breast cancer
Patients were randomized to standard physiotherapy or standard physiotherapy plus the relaxation program after surgery for breast cancer. Physiotherapy was provided for one week. The experimental group also had one-hour group sessions daily in groups of three for one week. The program involved relaxation breathing exercises, visualization, and body scan, providing progressive muscle relaxation techniques. Those in the experimental group were given audiocassettes with instructions for home practice and were asked to do this daily for another three weeks.
There was significant reduction in anxiety in the experimental group (p < .01), while mean anxiety level in the control group remained essentially the same. State anxiety levels were significantly lower after physiotherapy and relaxation training in the experimental group compared to controls one hour after physiotherapy (p = .038).
Visualization and progressive muscle relaxation as provided in this program may help reduce anxiety after surgery among patients with breast cancer.
Relaxation therapy including visualization and progressive muscle relaxation as accomplished in this program may be helpful for patients to reduce anxiety. This study has limitations and does not provide strong support for effectiveness; however, these are very low-risk types of interventions that may be helpful to some patients.
Nunes, D.F., Rodriquez, A.L., DaSilva Hoffman, F., Luz, C., Braga Filho, A.P. Muller, M.C., & Bauer, M.E. (2007). Relaxation and guided imagery program in patients with breast cancer undergoing radiotherapy is not associated with neuroimmunomodulatory effects. Journal of Psychosomatic Research, 63, 647–655.
The relaxation intervention was a 30-minute, therapist-led group with relaxation and visualization therapy (RVT) consisting of relaxation, guided imagery, progressive muscle relaxation, meditation, and deep breathing. Each group had up to four patients. The intervention was delivered daily for 24 treatments immediately following radiation treatments. Patients self-administered the treatment at home using audiotapes twice per day. Patients received telephone calls to remind them to perform the intervention at home. Measures of psychological, endocrine, and immunologic data were collected at baseline and after the 24-day intervention.
The study reported on a sample of 34 women with breast cancer receiving radiation treatments (intervention group = 20; control group = 14).
A randomized controlled trial design was used.
Analyses were controlled for basal anxiety levels (trait anxiety). The psychological scores did not change over time in the control group, but the experimental group showed significantly reduced levels of stress, anxiety, and depression scores following the 24-day RVT treatment (all p < 0.05). Experimental and control groups showed similar stress and depression scores at baseline. Patients in the experimental group were more anxious than patients in the control group at baseline.
While no biologic changes were noted with RVT, there were significant improvements in psychological functioning with RVT.
The study had small sample sizes.
Sloman, R. (2002). Relaxation and imagery for anxiety and depression control in community patients with advanced cancer. Cancer Nursing, 25, 432–435.
The intervention involved progressive muscle relaxation (PMR) and guided imagery (GI). Patients were visited by a community RN who was trained in the use of relaxation and imaging technique. Tape recorders with cassettes were used to teach PMR and GI, with instructions provided by a clinical psychologist guiding the techniques.
Patients were randomized to one of four treatment groups:
A randomized controlled trial design was used.
The study had a small sample size.