Sodium sucrose octasulfate is a chemical compound. A similar compound, aluminum sucrose octasulfate (sucralfate), has been used clinically for the prevention of gastrointestinal ulcers and was found to have cytoprotective effects. The sodium and aluminum compounds are contents of various cosmetics for skin care.  Sodium sucrose octasulfate was evaluated in patients with cancer for the prevention and management of radiodermatitis.