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Date Palm Pollen

Date palm pollen is produced by flowers on male date palm trees. It has been investigated as a topically administered treatment for oral mucositis in patients with cancer. 

Dance/Dance Therapy

Dance or movement therapy is rhythmic body movement. Its use in therapy promotes spontaneous movement expression that can allow people to enact thoughts and feelings and reduce tension. Dance/movement therapy is the psychotherapeutic use of movement as a process that furthers the physical and psychological integration of individuals with cancer. Dance and movement therapy have been studied for their effects on anxiety, depression, and fatigue in patients with cancer.

Cyproterone Acetate

Cyproterone acetate is a synthetic steroidal antiandrogen drug used to treat prostate cancer. It suppresses androgen hormones by inhibiting growth of testosterone-sensitive cells. An acetate salt, the drug works by binding to androgen receptors to prevent receptor activation. Additionally, this drug reduces luteinizing hormone  via the pituitary gland, which reduces androgen secretion in the testes and overall serum testosterone levels. It has weak progestational and antineoplastic activities.


Cyproheptadine is an antihistamine marketed for the treatment of various allergic problems. Cyproheptadine is a serotonin and histamine antagonist with sedative and anticholinergic effects. In early clinical trials, cyproheptadine was noted to cause unexpected weight gain. It has been marketed in Europe as a drug for weight gain and evaluated for anorexia.

Cutaneous Stimulation

Cutaneous stimulation involves stimulation of nerves via skin contact in an effort to reduce pain impulses to the brain, based on the "gate control" theory of pain. A device used to provide electrocutaneous nerve stimulation was studied for its effect on symptoms of peripheral neuropathy.


The use of ice chips or ice-cold water has been studied for its efficacy in the prevention of oral mucositis. Patients suck on ice or hold ice-cold water in their mouths prior to, during, and after rapid infusions of mucotoxic agents with short half-lives. Cryotherapy is based on the theory that vasoconstriction caused by cold temperatures decreases the exposure of the oral cavity mucous membranes to mucotoxic agents. Thirty minutes of oral cryotherapy is suggested for patients receiving bolus 5-fluorouracil. Cryotherapy also has been used in patients receiving high-dose melphalan.


Cryoablation or cryosurgery is the use of extreme cold, generally produced by liquid nitrogen or argon gas, to destroy abnormal tissue. It has been used to treat some types of cancer as an alternative to surgery. Cryoablation has been studied for its effect on chronic, cancer-related pain.

Cranberry Juice

Cranberry juice contains chemicals with antioxidant properties and has been used as a home remedy for prevention of bladder infections. Cranberry juice was examined for its effectiveness in preventing urinary tract infections in patients with cancer undergoing pelvic radiation therapy.

COX-2 Inhibitors

COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug that directly affects COX-2, an enzyme involved in inflammation and associated pain. The use of COX-2 inhibitors was evaluated in patients with cancer related to the development of palmar-plantar erythrodysesthesia (PPE) skin effects and as a potential treatment for oral mucositis. Celecoxib, a type of COX-2 inhibitor, has also been studied for its impact on symptoms of depression in patients with cancer.

Couples Therapy

Couples therapy involves the provision of professional psychological counseling with focus on interpersonal processes and interactions to enhance relationship quality and intimacy. The intervention is provided to couples rather than to each individual separately. Couples therapy has been examined for its effects on caregiver strain and burden.

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