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Transcutaneous Electrical Nerve Stimulation (TENS)/Cutaneous Stimulation

Transcutaneous electrical nerve stimulation (TENS)/cutaneous stimulation is a process involving electrodes placed on the skin over muscles or nerves with a power device generating pulse widths of less than 70 mA (Forst, Nguyen, Forst, Disselhoff, Pohlmann, & Pfutzner, 2004). TENS specifically for patients with cancer has been studied related to pain management.

Transanal Drainage

Transanal drainage is used after an anterior resection for rectal cancer. A tube is inserted to help prevent anastomotic leakage and bleeding after surgery. 

Tranexamic Acid

Tranexamic acid is an antifibrinolytic agent that is a derivative of lysine. It inhibits activation of pathways that breakdown fibrin, which is a component of blood clots. It is similar to aminocaproic acid. It has been used to control hemorrhage following surgery and post-partum, and in hemophilia treatment. Tranexamic acid alone and in combination with aminocaproic acid has been evaluated in patients with cancer for the prevention and control of bleeding.

Tramadol

Tramadol is an analgesic used to relieve moderate to moderately severe pain. Tramadol, which is in a class of medications called opiate agonists, is available as a tablet and an extended-release (long-acting) tablet to take by mouth.

Topical Ketamine Formulations

Topical formulations containing amitriptyline and ketamine have been tested for effects on patients with chemotherapy-induced peripheral neuropathy. One of these formulations, BAK, also included baclofen.

Topical Anesthetics

The topical use of anesthetics consists of applying an anesthetic agent, such as lidocaine, to the skin or mucosa. In cancer care, topical anesthetics are used to reduce the acute pain of diagnostic procedures, such as biopsy, and postoperative incisions. Topical anesthetics have been examined in chronic pain as well

Tibolone

Tibolone is an anabolic steroid. Tibolone has been examined in the treatment of hot flashes.

Thyrotropin Releasing Hormone (TRH)

TRH is a hormone that stimulates release of thyroid-stimulating hormone from the pituitary gland. TRH has been studied in patients with cancer for its effect on fatigue.

Theta Cream 

Theta cream contains glucan, hydroxyprolisilane, and matrixyl. Glucan is a polysaccharide molecule, some types of which occur in nature in plants, grains, baker's yeast, and medicinal mushrooms. Some of these have modulating effects on the immune system. Hydroxyprolisilane is a component of several cosmetic skin care products that has properties of tissue regeneration and strengthening of collagen and elastin fibers. Matrixyl is in some anti-aging creams and serums.

Therapeutic Touch

Therapeutic touch (TT) or healing touch is an energy therapy where the practitioner’s hands move through the patient’s energy field to assess and treat energy field imbalances (Shames & Keegan, 2000). The specially trained practitioner deliberately “centers” intention from an external focus to an internal focus of calm, then moves his or her hands over the patient’s body, but does not actually touch the body. TT has been studied as an intervention for anxiety and pain in patients with cancer.

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