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At the time of diagnosis, 20%–75% of patients with cancer report having pain. Breakthrough pain is sudden, brief pain that occurs during a period when chronic pain is generally well controlled (typically, controlled with opioids). Breakthrough pain may happen when the patient is at rest or be related to activity or a change of position.
Research regarding the use of common opioid preparations for pain is not included in this evidence, because opioids are clearly known to be effective and meet criteria of Recommended for Practice because of effectiveness. Only new formulations or delivery methods are included for evidence categorization.
ONS staff researchers and clinical specialists have exhaustively assessed evidenced-based research from comprehensive sources to provide you our best recommendations on Symptom Interventions for your patients.