Cancer-related fatigue has been defined as a distressing, persistent, and subjective sense of tiredness or exhaustion that is not proportional to activity and interferes with usual function. Fatigue is one of the most common problems in patients with cancer. It may be related to the disease itself or cancer treatment and may continue beyond completion of treatment among long-term cancer survivors. Among people with cancer, 80% to 100% report experiencing fatigue. Fatigue may be an isolated problem or occur as one element in a cluster of symptoms, such as pain, depression, dyspnea, anorexia, and sleep disturbance.

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This topic was updated on January 21, 2016.

2011–2015 Authors

Sandra Anne Mitchell, PhD, CRNP, AOCN®, Mohammad Omar Alkaiyat, RN, CRC, CCRP, Jane C. Clark, PhD, RN, AOCN®, GNP-C, Regina M. DeGennaro, DNP, RN, AOCN®, CNL, Amy J. Hoffman, BSN, MSN, PhD, Karol Huenerberg, FNP-BC, APNP, AOCNP®, Patricia Poirier, PhD, RN, AOCN®, Carolene B. Robinson, RN, MA, AOCN®, CBCN®, Karen Stilwell, RN, MSN, CNS, OCN®, and Breanna M. Weisbrod, RN, OCN® 

ONS Staff: Margaret M. Irwin, PhD, RN, MN, Christine M. Maloney, BA, Kerri A. Moriarty, MLS, and Mark Vrabel, MLS, AHIP, ELS


2009 Authors

Sandra A. Mitchell, PhD, CRNP, AOCN®, and Susan L. Beck, APRN, PhD, AOCN®, FAAN

ONS Staff: Linda H. Eaton, MN, RN, AOCN®


2006 Authors

Sandra A. Mitchell, MScN, CRNP, AOCN®, Susan L. Beck, PhD, APRN, AOCN®, Linda Edwards Hood, MSN, RN, AOCN®, Katen Moore, MSN, APRN, AOCN®, and Ellen R. Tanner, RN, BSN, OCN®

ONS Staff: Linda H. Eaton, MN, RN, AOCN®

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