Blijlevens, N.M., Donnelly, J.P., Naber, A.H., Schattenberg, A.V., & DePauw, B.E. (2005). A randomised, double-blinded, placebo-controlled, pilot study of parenteral glutamine for allogeneic stem cell transplant patients. Supportive Care in Cancer, 13, 790–796.doi: 10.1007/s00520-005-0790-y
Parenteral nutrition supplemented with 0.57 g/kg glutamine-dipeptide was started on day 6 for a median of 19 days for patients in the treatment group.
The study was conducted between July 1999 and July 2002.
This was a randomized, double-blinded, placebo-controlled pilot study.
Oral assessment was conducted daily. Lesions, erythema, edema, pain, bleeding, dryness, and the production of viscous mucous were scored on a 0–3 scale and summed to produce a daily oral mucositis score (DMS).