Grunwald, V., Kalanovic, D., & Merseburger, A.S. (2010). Management of sunitinib-related adverse events: An evidence- and expert-based consensus approach. World Journal of Urology, 28, 343–351.doi: 10.1007/s00345-010-0565-z
To provide advice for patient care in daily practice regarding the management of side effects of sunitinib.
Information was compiled and clinical experts were asked to identify the degree to which they agreed or disagreed with the information. Those measures agreed on by 70% of respondents were included in this summary. Clinicians had to have cared for at least 30 patients receiving sunitinib. Twelve German clinical experts provided analysis.
Databases searched were PubMed, Embase, Current Contents, and recommendations of oncology societies.
Key topics were sunitinib and tyrosine kinase inhibitor therapy management recommendations.
Nausea and Vomiting:
Erythema, Dry Skin, and Dermatitis:
A significant need exists for more scientific evidence on the prevention and management of side effects caused by these agents for cancer treatment.