Kawazoe, H., Motoki, Y., Takechi, Y., Shishino, Y., Ido, K., Suemaru, K., & Araki, H. (2010). Comparison of antiemetic efficacy between single and repeat treatment with dexamethasone in patients receiving carboplatin-based combination chemotherapy. Methods and Findings in Experimental and Clinical Pharmacology, 32(7), 499-505.doi: 10.1358/mf.2010.32.7.1501438
To assess the preventive effects of single and repeat treatment with dexamethasone on delayed nausea and vomiting in patients receiving carboplatin-based chemotherapy
This was a single-site study conducted at an inpatient setting in Ehime, Japan.
This was a retrospective, observational study.
Patients treated with carboplatin-based combination chemotherapy may benefit from a daily dose of dexamethasone for three days following initiation of chemotherapy.