Edwards, S.J. (2003). Prevention and treatment of adverse effects related to chemotherapy for recurrent ovarian cancer. Seminars in Oncology Nursing, 19(3, Suppl. 1), 19–39.
Multiple interventions can be implemented to prevent or minimize PPE. Patient education is an integral component to promote self-care. Key teaching points include strategies for patients to avoid pressure and friction on their skin because those behaviors may increase uptake of the affecting drug into the blood vessels of the hands and feet.
Routine assessment for PPE should include examination of the palms and soles for redness, swelling, flaking, blisters, rash, sores, cracks, and fissures. Based on nursing assessment, dose modifications may be needed.