Grunberg, S., Chua, D., Maru, A., Dinis, J., DeVandry, S., Boice, J.A., … Herrstedt, J. (2011). Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: Randomized, double-blind study protocol—EASE. Journal of Clinical Oncology, 29, 1495–1501.doi: 10.1200/JCO.2010.31.7859
To evaluate the effectiveness of a single dose of fosaprepitant in combination with dexamethasone and 5-HT3 for chemotherapy-induced nausea and vomiting (CINV)
The study was conducted at multiple outpatient settings in 27 different countries.
All patients were in active treatment.
The study was a double-blind, randomized-controlled, parallel group.
The following measurement tools were used.