Kim, S., Shin, I., Kim, J., Kim, Y., Kim, K., Kim, K., … Yoon, J. (2008). Effectiveness of mirtazapine for nausea and insomnia in cancer patients with depression. Psychiatry and Clinical Neurosciences, 62, 75-83.doi: 10.1111%2Fj.1440-1819.2007.01778.x
To evaluate the effectiveness of mirtazapine for nausea and insomnia in patients with cancer with depression
Assessments were conducted at baseline and on days 1, 3, 5, 7, 14, and 28 by trained psychiatrists in an outpatient clinic. In addition, side effects were assessed with each visit. This was a four-week study.
Participants were recruited from a university cancer center in Korea.
This was a prospective, open-label study.
The following measurement tools were used.
Mirtazapine rapidly improved nausea, sleep disturbance, pain, depression, and quality of life for patients with cancer.