Bleeding in patients with cancer results from an interplay of disease- and treatment-related factors. Certain types of cancer such as leukemia have a higher probability of bleeding, with up to 90% of patients with acute promyelocytic leukemia developing hemorrhagic complications. Thrombocytopenia can be caused by chemotherapy or radiation therapy as well as infection, disseminated intravascular coagulation, liver disease, and platelet dysfunction.
ONS PEP resources address only interventions that prevent, reduce, or manage bleeding directly related to cancer and/or its treatment. Because little new evidence is available in this area, the resources are pending updates. Current evidence provided is through May 2008.
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