Targeted Therapy Resources

Targeted Therapy Resources

Targeted therapy is about identifying features of cancer cells that are different than normal cells. Scientists use this information to create a targeted therapy that will attack cancer cells without damaging the normal cells, thus leading to fewer side effects.

Targeted therapies work by:

  1. Blocking angiogenesis
  2. Blocking signals inside or outside the cell
  3. Delivering toxic substances to the cell

Challenges of targeted therapy

Using a drug that works on your specific cancer may seem simple. But targeted therapy is complicated and not always effective. It is important to remember that:

  • A targeted treatment will not work if the tumor does not have the target.
  • Having the target does not mean the tumor will respond to the drug.

Metastatic Breast Cancer Therapy

  • The Clinical Journal of Oncology Nursing has many articles on targeted therapies that include Implications for practice, management of adverse reactions, and practice recommendations. Many of these articles offer CNE.

*The creation of these resources is being supported by an educational grant through Pfizer.

Targeted therapies are currently the focus of anticancer drug development. They are a cornerstone of precision medicine, a form of medicine that uses information about a person’s genes and proteins to prevent, diagnose, and treat disease. Many targeted cancer therapies have been approved or fast tracked for approval by the Food and Drug Administration (FDA) to treat specific types of cancer.

You can find a list of targeted therapies and their target here.

Recognize It; Report It:

Nurses should use appropriate assessment tools to recognize adverse events experienced by patients on investigational or newly approved agents.  After communicating with the healthcare team, if a higher level of awareness is necessary, side effects should be reported to the FDA Medwatch program.

Patient Education Resources 

Utilize Oral Chemotherapy Education (OCE) sheets as a free educational resource for patients with cancer in need of concise, easy-to-understand information about oral cancer drugs.