Communication, Organization Are Top Drivers of Oral Adherence in Clinical Trials

Oncology nurses know the challenges of patient adherence to oral cancer therapies. Every dose a patient misses can affect their outcomes and chance of survival. But in clinical trials, oral adherence has even broader implications: when a study is evaluating the efficacy of a drug, it depends on study participants taking it exactly as the trial outlines. 

In their article in the June 2018 issue of the Clinical Journal of Oncology Nursing, Gborogen and Polek discussed the problem of oral adherence in clinical trials, the implications of nonadherence, and the results of their study to determine the key sources of nonadherence at the patient, nurse, physician, and other levels.