A Nursing Intervention for Reducing Symptom Burden During Chemotherapy

Annemarie Coolbrandt, RN, PhD; Hans Wildiers, MD, PhD; Annouschka Laenen, PhD; Bert Aertgeerts, MD, PhD; Bernadette Dierckx de Casterlé, RN, PhD; Theo van Achterberg, RN, PhD; Koen Milisen, RN, PhD


Objectives: To evaluate the efficacy of an individually tailored nursing intervention for reducing chemotherapy-related symptom distress in adult patients with cancer. 

Sample & Setting: A control group (n = 71) received usual care and an intervention group (n = 72) received usual care and the CHEMO-SUPPORT intervention, all at the University Hospitals of Leuven in Belgium.

Methods & Variables: The intervention effect was evaluated by measuring the difference in outcomes between the two groups. The primary outcome, overall symptom distress, and other symptom-related outcomes were self-reported at the start of treatment (baseline) and at 3, 6, and 12 weeks.

Results: The CHEMO-SUPPORT intervention showed significantly less worsening of overall symptom distress and severity. Self-efficacy and outcome expectations (measured at six weeks) were significantly higher in the intervention group. Self-care (measured at 12 weeks) was statistically similar between the two groups. The results emphasize the importance of nurses in coaching patients to adequately self-manage their symptoms at home.

Implications for Nursing: Providing goal-directed self-management support using motivational interviewing as well as tailoring are promising areas for reducing chemotherapy-related symptom distress.

View Article @ onf.ons.org

ONS Voice Articles

Dive into a rich source of oncology nursing expertise with ONS articles.

View All Voice Articles