Mentes, S.D., Unsal, D., Baran, O., Argun, G., & Ertunc, F.N. (2005). Effect of sedation with midazolam or propofol on patient’s comfort during cancer chemotherapy: A prospective, randomized, double-blind study in breast cancer patients. Journal of Chemotherapy, 17, 327–333.
Intervention Characteristics/Basic Study Process
The trial had three arms: Group 1 – chemotherapy control, Group 2 – chemotherapy plus midazolam, and Group 3 – chemotherapy plus propofol.
Sample Characteristics
The study reported on a sample of 45 patients with breast cancer (s/p mastectomy, second chemotherapy).
Setting
Turkey
Study Design
A randomized controlled trial design was used.
Measurement Instruments/Methods
Clinical Global Impression Scale (CGI) for anxiety
Results
Midazolam and propofol significantly decreased anxiety, with propofol being better.
Limitations
It is unclear which groups completed the CGI measure.