Midtgaard, J., Rørth, M., Stelter, R., Tveterås, A., Andersen, C., Quist, M., . . . Adamsen, L. (2005). The impact of a multidimensional exercise program on self-reported anxiety and depression in cancer patients undergoing chemotherapy: A phase II study. Palliative and Supportive Care, 3, 197–208.

The intervention was a six-week, nine-hour weekly group intervention of high (exercise) and low (massage) intensity. “Talking time” also was included. A trained nurse and physiotherapist administered the intervention.

• The study reported on a sample of 91 patients.
• The sample was comprised of a heterogeneous cancer population receiving chemotherapy.

Denmark

A prospective follow-up design was used (one group, pre/post-test).

• Hospital Anxiety and Depression Scale (HADS) – depression and anxiety subscales
• Aerobic capacity

Anxiety and depression scores improved (p < 0.001). Patients who were physically nonactive improved more on the HADS anxiety subscale than those in the active group. Women improved more on the HADS anxiety subscale than men.

• The study was not randomized.
• The study did not include pharmacologic assessment.
• The sample was 70% female.