Sadja, J., & Mills, P.J. (2013). Effects of yoga interventions on fatigue in cancer patients and survivors: A systematic review of randomized controlled trials. Explore, 9, 232–243. 

DOI Link

Purpose

STUDY PURPOSE: To evaluate the evidence of effects of yoga on fatigue among cancer survivors

TYPE OF STUDY: Systematic review

Search Strategy

DATABASES USED: PubMed, PsychINFO; in addition, reference lists of articles included in review
 
KEYWORDS: (yoga or yougis or asana or prana) and (fatigue or exhause or burnout or letharf or wary or weariness or drows or tired) and (cancer or metastatic or leukemia or lymphoma or tumor or oncology or oncologist or malignant or malignancy or chemotherapy or radiation)
 
INCLUSION CRITERIA: Articles published in English accepted into publication into a peer-reviewed journal; participants are cancer survivors participating in randomized, controlled yoga interventions
 
EXCLUSION CRITERIA: Adjunctive interventions such as psychotherapy, nutrition, or medications; case studies, conference abstracts, and nonexperimental studies

Literature Evaluated

TOTAL REFERENCES RETRIEVED: 44
 
EVALUATION METHOD AND COMMENTS ON LITERATURE USED: Studies screened by the authors using standard data extraction form; risk of bias evaluated using Cochrane Collaboration tool

Sample Characteristics

  • FINAL NUMBER STUDIES INCLUDED = 10
  • TOTAL PATIENTS INCLUDED IN REVIEW = 583
  • SAMPLE RANGE ACROSS STUDIES: 18–164
  • KEY SAMPLE CHARACTERISTICS: 564 women, 17 men; primarily breast cancer; 80%–100% Caucasian, with the exception of one study with 42% African-American, 31% Hispanic, 23% Caucasian, and 4% other 

Phase of Care and Clinical Applications

PHASE OF CARE: Transition phase after active treatment

Results

Eight of 10 studies only had patients with breast cancer; various stages of cancer; no standard type of yoga intervention; little consistency in measuring fatigue; high risk of selection bias in included studies. In four studies the yoga group reported significant reduction in CRF; three studies reported that there were significant reductions in participants who attended a significant number of classes; four studies reported no differences in self-reported fatigue and no association with number of classes attended.

Conclusions

The authors suggest that yoga may be beneficial for CRF but urge caution. Small sample sizes and lack of standardization affect ability to draw conclusions. None of the studies reported increase in fatigue, thus no evidence that yoga is detrimental. Evidence of significant reduction of fatigue with number of classes attended.

Limitations

  • Small number of studies
  • Primarily women with breast cancer
  • Methodological bias in many studies

Nursing Implications

There is suggestion that yoga may be beneficial; therefore, nurses can recommend this to appropriate individuals. Adherence impacts effect; therefore, it is important that the choice of activity fit with an individual’s lifestyle. More well-conducted studies are needed.

Legacy ID

4036