Xiao, F., Song, X., Chen, Q., Dai, Y., Xu, R., Qiu, C., & Guo, Q. (2016). Effectiveness of psychological interventions on depression in patients after breast cancer surgery: A meta-analysis of randomized controlled trials. Clinical Breast Cancer. Advance online publication. 

DOI Link

Purpose

STUDY PURPOSE: To assess the effectiveness of Cognitive Behavioral Therapy (CBT) or CBT approach interventions for improving depressive symptoms

TYPE OF STUDY: Meta-analysis and systematic review

Search Strategy

DATABASES USED: Medline, PubMed, Cochrane Collaboration, WANFANG, CNKI database
 
INCLUSION CRITERIA: Randomized, controlled trials; comparison of an individual CBT intervention to a control group; women with breast cancer
 
EXCLUSION CRITERIA: None specified

Literature Evaluated

TOTAL REFERENCES RETRIEVED: 1,882
 
EVALUATION METHOD AND COMMENTS ON LITERATURE USED: Jadad scale for methodologic study quality

Sample Characteristics

  • FINAL NUMBER STUDIES INCLUDED = 13 
  • TOTAL PATIENTS INCLUDED IN REVIEW = 966
  • SAMPLE RANGE ACROSS STUDIES: Not provided
  • KEY SAMPLE CHARACTERISTICS: Women with breast cancer who had undergone surgery

Phase of Care and Clinical Applications

PHASE OF CARE: Not specified or not applicable

Results

Analysis was conducted for each type of outcome measurement instrument used in the research. Across eight studies using the Self-Rating Depression Scale (SDS), the effect of the intervention was seen to be beneficial (standard mean difference [SMD] = –0.87, p < 0.0001). The pooled results of three studies for effects using the Hospital Anxiety and Depression Score (HADS) was also in favor of the intervention (SMD = –0.50, p = 0.04). Across all studies, the SMD comparing CBT to control was –0.92 (p < 0.00001).

Conclusions

Individually delivered CBT was shown to be effective in reducing the symptoms of depression among women with breast cancer.

Limitations

In some studies, different cognitive behavioral approaches were used, and some delivered the intervention via a combination of face-to-face and telephonic contact. The results of the study quality evaluation were not reported. All studies excluded patients with major depression diagnoses.

Nursing Implications

Interventions using cognitive behavioral approaches can be effective to reduce the symptoms of depression in women having undergone surgery for breast cancer. Although full CBT is generally delivered by trained therapists, nurses can incorporate many of these principles into general patient teaching, counseling, and support. Patients with significant depression should be referred for appropriate management as needed.

Legacy ID

6288