Peripheral nerve block refers to the use of local anesthetics to block peripheral nerves, which blocks the signaling of pain stimuli from the tumor to the central nervous system (Klepstad et al., 2015; Swarm, Karanikolas, & Cousins, 2000). This intervention has been studied for treatment of cancer-related pain. 

Klepstad, P., Kurita, G.P., Mercadante, S., & Sjogren, P. (2015). Evidence of peripheral nerve blocks for cancer-related pain: A systematic review. Minerva Anestesiologica, 81, 789–793.  Retrieved from https://www.minervamedica.it/en/journals/minerva-anestesiologica/articl…  

Swarm, R.A., Karanikolas, M., Cousins, M.J. (2000). Injections, neural blockade, and implant therapies for pain control. In G. Hanks, N. Cherny, N. Christakis, M. Fallon, S. Kaasa, & R.K. Portenoy (Eds.), Oxford Textbook of Palliative Medicine (pp. 734-755). Oxford, UK: Oxford University Press.