Cell Transplant
Direct, local cell transplants have been tested for effects on cancer-related lymphedema. Stromal cells obtained from the bone marrow are stem cells that can differentiate into various cell types, potentially including lymphatic cell types. In the process of stromal cell transplantation, autologous stromal cells were transplanted around the axillary region and affected areas of the chest wall in patients who had previous breast cancer surgery and radiation therapy to evaluate effect on lymphedema.
Celiac Plexus Block
A celiac plexus block is a procedure that damages the celiac nerves with the intent to ease pain. A celiac plexus block can be performed during surgery, during an endoscopic ultrasound (EUS), or by using a percutaneous approach (i.e., going through the skin). In all cases, a doctor will first inject an anesthetic to numb the celiac nerves and then inject a substance to damage the nerves. The effects of the anesthetic are almost instantaneous but are not long lasting.
Celiac Ganglion Irradiation
Celiac ganglion irradiation via implantation of iodine-125 seeds into the celiac ganglion was examined in patients with chronic pain from pancreatic cancer. Because radioactive rays injure neural tissue, this approach is a potential alternative way to accomplish neurolysis for pancreatic pain.
Cat's Claw (Uncaria tomentosa, Uncaria guianesis)
Cat's claw is a wood vine that grows wild in central and South America, particularly in the Amazon rainforest. Historically, cat's claw has been used to prevent and treat disease dating back to the Inca civilization. Its inner bark is used to make liquids, capsules, and teas, and preparations can be applied to the skin. Cat's claw may have some properties to boost the immune system and reduce inflammation. Cat's claw has been examined for its effects on sleep-wake disturbances, fatigue, anxiety, and depression in patients with cancer.
Catheter Care Bundle for Prevention of Central Line Associated Infection (CLABSI)
A catheter care “bundle” includes the provision of care using a standard combination of interventions to prevent central line associated blood stream infections (CLABSIs). This combination includes hand hygiene, use of maximum sterile barriers at line insertion, cleansing the insertion site with chlorhexidine, avoiding use of the femoral and jugular sites for line insertion, and prompt removal of unnecessary catheters.
Carnitine/L-Carnitine
Acetyl-l-carnitine (γ-trimethyl-β-acetylbutyrobetaine [ALC]) is the acetyl ester of carnitine. ALC is present throughout the central and peripheral nervous systems, plays an essential role in the oxidation of free fatty acids, and has displayed neuroprotective properties. Carnitine is available without a prescription as a dietary supplement, and is found in highest concentrations in red meat and dairy products.
Caregiver/Partner Interventions
Caregiver/partner interventions refer to provision of a specific intervention to a patient’s informal caregiver, spouse, or partner in an attempt to affect the patient's symptoms. Caregiver/partner interventions involving education and enhancing partner adjustment to the patient’s illness have been studied in patients with cancer in an attempt to manage patient anxiety.
Caregiver Training and Skill Development
Caregiver training and skill development is the provision of education and training to develop technical and other caregiving skills and to enhance knowledge involved in assuming the caregiver role.
Carbamazepine
Carbamazepine is used alone or with other medications in the treatment of certain types of seizures. Carbamazepine also is used to treat trigeminal neuralgia (a condition that causes facial nerve pain) and is an anticonvulsant that works by reducing abnormal electrical activity in the brain. Carbamazepine is available as a tablet, a chewable tablet, an extended-release tablet, an extended-release capsule, and a suspension (liquid) to take by mouth. Carbamazepine has been studied related to chemotherapy-induced nausea and vomiting (CINV) and peripheral neuropathy.
Camellia and Wheat Extract
Camellia sinensis leaf extract is derived from green tea and has antioxidative properties. Palmitoyl hydrolyzed wheat protein is a condensation product of palmitic acid chloride and hydrolyzed wheat protein. This protein is believed to have healing properties for skin and mucosa. Camellia sinensis leaf extract and palmitoyl hydrolyzed wheat protein are active ingredients in Baxidil Onco®, which has been studied in patients with cancer to treat oral mucositis.